povidone iodine nasal spray formulation

About Mundipharma, When povidone iodine, the active ingredient in, Kills 99.99% of sore throat-causing Viruses and bacteria in as early as 30 seconds, M093P020123BS, M081P021323BS, M076P021023BS. Laryngoscope. FLCCC 1% Iodine Nasal Irrigation Tutorial. Virucidal Effect of Povidone Iodine on SARS-CoV-2 in Nasopharynx: An Open-label Randomized Clinical Trial. Remove cap. (2) CofixRX Nasal Spray Povidone Iodine 1.25% Nasal Spray Xylitol FREE In vitro inactivation of SARS-CoV-2 with 0.5% povidone iodine nasal Administrative, technical, or material support: Guenezan, Garcia, Jousselin. Nawaz M, Ashraf MA, Ali MA, Shabbir MZ, Shabbir MAB, Altaf I, Raza S, Rafique S, Hassan S, Sardar N, Mehmood A, Aziz MW, Fazal S, Khan MT, Atique HMM, Asif A, Ullah Z, Iqbal M, Imtiaz T, Anwar M, Mukhtar N, Yaqub T. Life (Basel). the. 3. Watch Video Tutorial Here: 1% Povidone Iodine DIY How To Video. Steps to reduce risk transmission risk from these sources could minimise the overall impact on the healthcare system by reducing transmission from patients to healthcare workers. "It's odd because there's so much evidence for the vaccine, but people are turning to povidone-iodine" said Dr. Adalja. 2022;123:179-181. doi:10.1016/j.jhin.2022.01.001, Zarabanda D, Vukkadala N, Phillips K, QianJ, Mfuh K O, et al. Read our. These tiny drops from a person move through the air and land on the mouths or noses of others nearby. Germs spread from person to person mainly in droplets that fly out when you cough or sneeze. No safety-relevant finding or serious adverse events were reported, no evidence for cyto- nor genotoxicity obtained. prescription at any drug store for a few dollars. In vitro inactivation of SARS-CoV-2 with 0.5% povidone iodine nasal spray (Nasodine) at clinically relevant concentrations and . Nasodine is a commercial formulation of 0.5% PVP-I that has been evaluated for safety and efficacy in human trials as a treatment for the common cold, including a Phase III trial (ANZCTR: ACTRN12619000764134). ORL; Kanagalingam J, Feliciano R, Hah JH, Labib H, Le TA, Lin JC. 3. Ramya has a Ph.D. in Biotechnology from the National Chemical Laboratories (CSIR-NCL), in Pune. Frank S, Capriotti J, Brown SM, Tessema B. The best, safest evidence-based methods for preventing COVID-19 (and staving off severe disease and hospitalization) remain to be vaccination and masking. Compilation of the top interviews, articles, and news in the last year. Follow-up was done on day 1 and then every 2 days until day 7 to assess the efficacy (viral quantification) and safety of the decolonization. Nasodine Nasal Spray is based on povidone-iodine, the same active ingredient found in Betadine throat gargle, and has been in development for almost a decade as a treatment for the common cold. Epub 2008 Apr 18. For nasal application to skin inside of nostrils in adults and children 3 years of age and older: 1. Can povidone iodine gargle/mouthrinse inactivate SARS-CoV-2 and decrease the risk of nosocomial and community transmission during the COVID-19 pandemic? Zarabanda D, Vukkadala N, Phillips KM, Qian ZJ, Mfuh KO, Hatter MJ, Lee IT, Rao VK, Hwang PH, Domb G, Patel ZM, Pinsky BA, Nayak JV. Povidone Iodine Mouthwash, Gargle, and Nasal Spray to Reduce Nasopharyngeal Viral Load in Patients With COVID-19: A Randomized Clinical Trial. Price and other details may vary based on product size and colour. 2021. Ear Nose Throat J. - Tilt head back, apply 4-5 drops to . 2022 Sep 13;12(9):1424. doi: 10.3390/life12091424. as 30 seconds.85, Helps relieve 7 signs and symptoms of a sore throat.113, 5 benefits in 1 - Scientifically demonstrated to kill common viruses, bacteria, fungi, spores and microscopic parasites that causes sore.85,114,.115. This study evaluated nasal and oral antiseptic formulations of PVP-I for virucidal activity against SARS-CoV-2. Laryngoscope. Ear Nose Throat J. You can find out more about our use, change your default settings, and withdraw your consent at any time with effect for the future by visiting Cookies Settings, which can also be found in the footer of the site. Posted in: Medical Research News | Disease/Infection News | Pharmaceutical News, Tags: Allergic Contact Dermatitis, Coronavirus, Coronavirus Disease COVID-19, Coughing, covid-19, Decontamination, Dermatitis, Efficacy, in vivo, Maxillofacial, Respiratory, SARS, SARS-CoV-2, Severe Acute Respiratory, Severe Acute Respiratory Syndrome, Skin, Sneezing, Surgery, Syndrome, Thyroid, Virus. RNA indicates ribonucleic acid; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; TCID50, tissue culture infectious dose. Povidone Iodine (PVP-I) Oro-Nasal Spray: An Effective Shield for COVID Firebrick Pharma files Pediatric Investigation Plan for Nasodine It's not clear where the idea that Betadine could potentially prevent COVID-19 came from in the first place. All Rights Reserved, Challenges in Clinical Electrocardiography, Clinical Implications of Basic Neuroscience, Health Care Economics, Insurance, Payment, Scientific Discovery and the Future of Medicine, 2021;147(4):400-401. doi:10.1001/jamaoto.2020.5490. We propose in this SBIR Phase I to optimize an in-situ gel forming nasal spray formulation containing both povidone iodine and budesonide by using polysaccharide gel matrix, where the effective concentrations of drug substances are maintained by the equilibrium between solution drug substances and the gel bound components resulting in a long . Explanation could be humidification, improved surfactant (phospholipid) level and/or sufficient mucolytic activity of iodide due to local application of the constituents. Epub 2020 Jul 24. Epub 2020 Jun 16. Iodine 1% Nasal Spray is part of the FLCCC I-CARE early treatment protocol : Nasal spray with 1% povidone-iodine: 2-3 times a day. THROAT SPRAY. And I see someone else asked for help with making the solution & you didn't reply. Correctives 0.1-3%. Dr Peter McCullough: Nasal Spray and Mouth Gargle to stop COVID? Bethesda, MD 20894, Web Policies Recommendation of the German Society of Hospital Hygiene (DGKH): Prevention of COVID-19 by virucidal gargling and virucidal nasal spray - updated version April 2022. . Add to List. Povidone Iodine nasal spray and throat spray helps cleanse away allergens, germs, viruses & bacteria to relieve symptoms from infections, chronic sinusitis & allergies. In Vitro Efficacy of a Povidone-Iodine Nasal Antiseptic for Rapid Inactivation of SARS-CoV-2 . All Rights Reserved. Povidone iodine: Basics, Side Effects & Reviews - GoodRx Can Anal Swabs Be Used to Test for Coronavirus? Povidone Iodine Mouthwash, Gargle, and Nasal Spray to Reduce Nasopharyngeal V iral Load in Patients With COVID-19: A Randomized C linical Trial. Ingesting povidone-iodine can pose health risks. Epub 2020 Dec 8. Iodine derivative kills SARS-CoV-2 within 90 sec. 10% Povidone Iodine is available OTC (Over the Counter) without a (2021, July 19). Povidone-iodine | Drugs | BNF | NICE Gently blow nose to clear both nostrils. DIY 1 % Povidone Iodine Nasal Spray & Gargle Recipe And he hasn't returned so doesn't know of the now 2 comments awaiting his response. Conclusions: Limitations include the small number of patients and the single-center design. DIY 1% Povidone Iodine. In vitro efficacy of a povidone-iodine nasal antiseptic for rapid inactivation of SARS-CoV-2. Health.com uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. 2022. Share. PDF Kirk Bailey - McGill University Betadine (Povidone Iodine): Price and Reviews 2022 - Aesthetics Advisor Ashley Abramson is a freelance writer based in Milwaukee, WI. JAMA Otolaryngol Head Neck Surg. Researchers discovered that there was a SARS-CoV-2 viral load reduction in all individuals from the 2021 study. Owned and operated by AZoNetwork, 2000-2023. "After a 25-minute contact time, the nasal spray reduced virus from 4.2 to 1.7 log10 CCID50 per 0.1 Read more 19 Best Quercetin and Bromelain Benefits 2023. National Library of Medicine In this interview, AZoM speaks to Rohan Thakur, the President of Life Science Mass Spectrometry at Bruker, about what the opportunities of the market are and how Bruker is planning on rising to the challenge. (2020) The Use of Povidone Iodine Nasal Spray and Mouthwash During the Current COVID-19 Pandemic May Reduce Cross . "There is evidence of toxicity to nasal epithelial cells with alcohol, benzalkonium chloride, and concentrations of povidone-iodine above 2.5%," Barone says. Epub 2022 May 6. We included adult outpatients (18 years old) having tested highly positive (cycle threshold 20) for SARS-CoV-2 ribonucleic acid (RNA) by reverse transcription-polymerase chain reaction (RT-PCR) in nasopharyngeal swabs within the previous 48 hours. Test compounds were evaluated for ability to inactivate SARS-CoV-2 as measured in a virucidal assay. The study was approved by the South Mediterranean Institutional Review Board, and written informed consent was obtained from all participants. Results: Further, Betadine's manufacturer, Avrio Health, has also warned customers against using Betadine to prevent COVID-19. NF, Klatt-Cromwell Kamal Arefin M, Banu SS, Nasir Uddin AKM, Nurul Fattah Rumi SK, Khan M, Kaiser A, Arafat MS, Chowdhury JA, Khan MAS, Hasan MJ. Spit out the solution. S, Bal Betadine also has an antiseptic throat gargle made with 0.5% PVP-I, but it's only meant to treat and relieve symptoms of a sore throat. FOIA FOIA Human-to-human transmission occurs mainly through the aerosolization of respiratory droplets. HC. You may use rubbing alcohol to remove staining from your skin. Jpn. Germs and allergens enter our airways by way of aerosol and droplets. Dwivedi, Ramya. Country . CofixRx, LLC - 626860 - 04/05/2022 | FDA Search Results For : " WWW EXTREME GAMING88 COM REGIS Use of PI had no influence on changes of viral RNA quantification over time (Figure). Unable to load your collection due to an error, Unable to load your delegates due to an error. "High doses of povidone-iodine could also cause kidney problems," added Dr. Adalja, along with potentially interfering with thyroid function. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. Considerations for povidone-iodine antisepsis in pediatric nasal and pharyngeal surgery during the COVID-19 pandemic. Box Plots Indicating Median, Interquartile Range, and 5th and 95th Percentiles, by Treatment Group, Table. In this work, Dr. Knts found that Iodine-V, which is currently available as the EID formulation, inactivated 99% of SARS-CoV-2 after 60 and 90 seconds. Would you like email updates of new search results? Another study indicated that gargling with PVP-I resulted in salivary SARS-CoV-2 suppression for 60 minutes. 28 Clinically, chronic topical use of concentrations up to 5% when used daily have been demonstrated to not result in thyroid disease. Povidone Iodine (PVP-I) Oro-Nasal Spray: An Effective Shield for COVID-19 Protection for Health Care Worker (HCW), for all. She's written for the New York Times, Washington Post, The Guardian, and more. , Frank Povidone Iodine - an overview | ScienceDirect Topics There is, of course, another danger too: It's that people are using remedies like povidone-iodine instead of the vaccinewhich is proven to work. You have us make a mug of your salt solution, then say to "snort that mugful into your nose" from your palms. If 1% product is not available, dilute the more widely available 10% solution and apply 4-5 drops to each nostril every 4 hours. SM, Capriotti Human clinical trials showed the product to be superior to other iodine formulations. A, Cheng A natural mineral made by earth. Rapid In-Vitro Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Using Povidone-Iodine Oral Antiseptic Rinse. et al. 2023 American Medical Association. Efficacy of Povidone-Iodine Nasal and Oral Antiseptic - PubMed Betadine is the brand name for a chemical compound called povidone-iodine (PVP-I) or iodopovidone. %PDF-1.6 % Chumpitaz-Cerrate V, Chvez-Rimache L, Ruiz-Ramirez E, Franco-Quino C, Erazo-Paredes C. J Int Soc Prev Community Dent. Always seek the advice of your physician or qualified healthcare provider with any questions you may have regarding any medical condition. A diluted iodine solution is a useful resource around the house, and even outside of it. Frank S, Capriotti J, Brown SM, Tessema B. JB, Pelletier Patients with a history of thyroid disease were excluded. Supervision: Guenezan, Strasters, Lvque, Frasca, Mimoz. They looked at the evidence of the gargle's virus-killing aspects in relation to COVID-19. In Singapore, a small National University Health System study found a 25% reduction in SARS-CoV-2 infection among those using the povidone-iodine nasal spray three times a day. 2020 Nov;99(9):586-593. doi: 10.1177/0145561320932318. ANTISEPTIC NASAL SPRAY, .5% POVIDONE IODINE USP ANTISEPTIC NASAL SPRAY, and 1.5% POVIDONE IODINE USP ANTISEPTIC THROAT SPRAY also do not conform to any temporary policy FDA has implemented during the public health emergency. In April 2022, Firebrick initiated a Phase 2 study of Nasodine for the treatment of COVID-19. Direct to throat delivery. Abstract SummaryWe propose to develop a long acting in situ gel nasal spray containing povidone iodine in combination with budesonide for the treatment of chronic rhinosinusitisChronic rhinosinusitisCRSis often the result of mixed inflammatory and infectious processes that concurrently affect the nose and para nasal sinusesThe condition is . Being excipient-free, this data also suggests that Iodine-V is likely to have better stability and an enhanced potency in vivo when compared with PVP-I. 8600 Rockville Pike with the formulations described in these . An evidence-based update, Gargling with povidone iodine has a short-term inhibitory effect on SARS-CoV-2 in patients with COVID-19, The Effect of Povidone-Iodine Nasal Spray on Nasopharyngeal SARS-CoV-2 Viral Load: A Randomized Control Trial. Pour Povidone-Iodine (BETADINE) Gargle & Mouthwash into the cup. The trial protocol is included in Supplement 1. Infected respiratory droplets can be produced during talking, sneezing, coughing, and panting by an infected individual, and can remain viable in aerosols for up to 3 hours. Close one nostril and put only the tip of spray nozzle in other nostril. Search Results For : " 2000Q4120051.NJR An oro-nasal spray is designed to apply the PVP-I in the nose and oral cavity to gain a protective layer or coating over nasal . PDF relevant concentrations and timeframes using tissue culture - bioRxiv https://www.news-medical.net/news/20210719/Iodine-derivative-kills-SARS-CoV-2-within-90-sec.aspx. 2022 Oct;74(Suppl 2):3534-3535. doi: 10.1007/s12070-022-03149-3. As such, we feel it is important that nasal administration of povidone-iodine is of at least as much importance as oral/oropharyngeal treatment. 10 Best Nasal Sprays for COVID-19 (2023) - Aesthetics Advisor Are There Dangers in Betadine Gargle or Nasal Spray? However, there was not a significant difference in the viral reduction between the different groups. Efficacy of Povidone-Iodine Nasal and Oral Antiseptic Preparations Efficacy of Mouth Rinses and Nasal Spray in the Inactivation of SARS-CoV-2: A Systematic Review and Meta-Analysis of. "People are looking for a quick and easy fix," said Dr. Pierre. Indian J Otolaryngol Head Neck Surg. The improved safety profile of EID is largely due to the significantly lower amount of iodine present in this formulation as compared to that which is found in PVP-I. All liposomal formulations had a positive effect on the nasal mucosa, challenged by allergy in some volunteers. Accessibility Statement, Our website uses cookies to enhance your experience. 2022 Sep 25;19(19):12148. doi: 10.3390/ijerph191912148. Iodine derivative kills SARS-CoV-2 within 90 sec. Discard tissue. sharing sensitive information, make sure youre on a federal In this interview, we speak to Ceri Wiggins, a Director at AstraZeneca, about the many applications of CRISPR and its role in discovering new COPD therapies. Iodine Mouthwash, Povidone, Antiseptic Wash and Gargle for prevention of Covid-19. Methods: Povidone iodine nasal antiseptic formulations and PVP-I oral rinse antiseptic formulations from 1% to 5% concentrations as well as controls were studied for virucidal efficacy against the SARS-CoV-2. Compounds for Targeted Degradation of Brd9 Amesh A. Adalja, MD, a senior scholar at the Johns Hopkins Center for Health Security," points out that Betadine is a brownish liquid solution often used as a topical antiseptic. In Vitro Efficacy of a Povidone-Iodine Nasal Antiseptic for Rapid Inactivation of SARS-CoV-2. To assess the virucidal effect of povidone iodine (PVP-I) on severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) located in the nasopharynx and suitable dose-formulation for nasal application were the purpose of this clinical trial. Intensive research efforts have led to the formulation of effective vaccines, 1 but human-to-human transmission of SARS-CoV-2 remains widespread. We also package all formulas in glass to ensure no leaching of chemicals. CofixRX nasal spray combines 1.25% povidone-iodine with vitamin D3. There appears to be no reliable data that suggests that povidone-iodine can help prevent COVID-19 or its spread, Cassandra M. Pierre, MD, MPH, an infectious disease physician and the medical director of public health programs at Boston Medical Center, told Health in September 2021. EPOTHEX Povidone Iodine Nasal Spray (0.6%) - Powerful Nasal Cleanser & Sinus Protection - Reduce Exposure to Airborne Contaminants - Travel Friendly - 30ml. Did you really mean for us to snort up the entire "mugful" each time, or just a few snorts? Dr. McCullough cites Amazon.com: Povidone Iodine Nasal Spray And Mouthwash By continuing to use our site, or clicking "Continue," you are agreeing to our, Figure. Introduction: SARS-CoV-2 was exposed directly to the test compound for 60 seconds, compounds were then neutralized, and surviving virus was quantified. Front Line Doctors Ivermectin Protocol for Prevention and Treatment of COVID-19 (November 2022), 12 Natural Treatments for COVID Long Haulers (2023), The Front Line COVID-19 Critical Care Alliance's (FLCCC's). Betadine Antiseptic Dry Powder First Aid Spray, Povidone-Iodine 5%, Infection Protection, Kills Germs in Minor Cuts Scrapes and Burns, No Mess, No Drip, No Sting Promise, No Alcohol, 2 . Disclaimer. We claim: 1. 2. Funding/Support: This project was supported by the University Hospital of Poitiers, France. Intervention consisted of 4 successive mouthwashes and gargles with 25 mL of 1% aqueous PI solution each (Mylan, Merignac, France), followed by one 2.5-mL nasal pulverization of the same solution into each nostril using an intranasal mucosal atomization device (MAD Nasal, Teleflex, Morrisville, North Carolina) connected to a 5-mL syringe while sniffing and 1 application on each nasal mucosa of a dab of 10% PI ointment followed by a massage of the nostril to help spread the ointment. Median (IQR) age of patients in the control group was 57 (45-68) years and in the intervention group was 33 (23-46) years. Type Small Molecule . Dr Peter McCullough: Povidone Iodine, Oral and Nasal Hygiene (2023) TTY users should call 1-800-718-4347. . All patients but 1 had negative viral titer by day 3. Kills 99.99% of sore throat-causing Viruses and bacteria in as early as 30 seconds 85. Povidone-iodine (Betadine) Gargle & Mouthwash It can sterilize routine cuts and scrapes, or clean skin before stitches or surgical procedures. Comparison of In Vitro Inactivation of SARS CoV-2 with Hydrogen Peroxide and Povidone-Iodine Oral Antiseptic Rinses. More specifically, an Intranasal Povidone-Iodine (PVP-I; 1.25%) spray has been found to be active against SARS-CoV-2, as well as SARS-CoV and the Middle East Respiratory Syndrome (MERS). J Prosthodont. VIRALDINE IS MADE WITH USP INGREDIENTS & CONTAINS NO DAMAGING SURFACTANTS OR ADDITIVES. The Effect of Povidone-Iodine Nasal Spray on Nasopharyngeal SARS-CoV-2 Viral Load: A Randomized Control Trial . Dent. Detailed Description: This will be a prospective single-blinded randomized placebo-controlled trial of two applications of a nasal 10% Povidone Iodine (PI) solution used on the intranasal mucosal surfaces of each nostril in the preoperative holding area within 2 h prior to surgical incision compared with NS using the same technique. Disclaimer. Never delay in seeking medical advice or disregard professional medical advice based on information provided on this website. Pls clarify what you meant to say.The 2 above points make me hope that you simply chose the wrong wording and will clarify. This medicine is also used as a surgical hand scrub and to wash the skin and surface of the eye before surgery to help prevent infections. 2. and transmitted securely. Find many great new & used options and get the best deals for (2) CofixRX Nasal Spray Povidone Iodine 1.25% Nasal Spray Xylitol FREE SHIP at the best online prices at eBay! 2022 Oct;74(Suppl 2):2906-2911. doi: 10.1007/s12070-021-02525-9. , Krber 1 cup of 0.9% Normal Saline (8 ounces) (See DIY Saline Post) 5 teaspoons 10% Povidone Iodine. Zoltn Knts, a researcher from IOI Investment Zrt., in Budapest, Hungary, recently demonstrated the efficacy of iodine against SARS-CoV-2 as a better alternative to Povidone-Iodine. Purpose of study: This phase I study assessed tolerability and local effect of a liposome dispersion with povidone-iodine (polyvinylpyrrolidone-iodine, PVP-I) as nasal spray. Do not use for more than 5 days in pregnancy. News-Medical. - Then fill to top with distilled, sterile or previously boiled water. the attention herein is directed to the nasal and oromucosal formulations intended to boost the local immunity, neutralize or . Knts, Z. He then moved to Royal Hospital London for post-doctoral training on clinical trial of . Saline Nasal Spray and Irrigation. Published Online: February 4, 2021. doi:10.1001/jamaoto.2020.5490. Clipboard, Search History, and several other advanced features are temporarily unavailable. main content Search Results For : "WWW EXTREME GAMING88 COM REGIS " e questions, call IEHP Member Services at 1-800-440-IEHP (4347), Monday-Friday, 7am-7pm, and Saturday-Sunday, 8am-5pm. News - iVIEW Therapeutics No modification in thyroid hormone (T3, T4) or creatinine levels was observed. This formulation will not only ensure patient comfort but also it will have the advantage of dual antiviral action with BAK and PVP-I [24]. Povidone iodine topical can stain skin, teeth, and fabric. This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply. How Long Does It Take for the COVID-19 Booster To Be Effective? Image Credit: bluecrayola / Shutterstock.com. Am J Otolaryngol. The Effect of Povidone-Iodine Nasal Spray on Nasopharyngeal SARS-CoV-2 Viral Load: A Randomized Control Trial. If 1% product is not available, dilute the more widely available 10% solution and apply 4-5 drops to each nostril every 4 hours. Safe and effective for peace of mind. Acquisition, analysis, or interpretation of data: All authors. Cookies collect information about your preferences and your devices and are used to make the site work as you expect it to, to understand how you interact with the site, and to show advertisements that are targeted to your interests. These data call for a larger clinical trial to confirm the benefit of PI in limiting the excretion and resulting human-to-human transmission of SARS-CoV-2, using lower PI concentrations to minimize adverse effects. 2020 Nov-Dec;41(6):102737. doi: 10.1016/j.amjoto.2020.102737. Viraldine is USP Povidone Iodine nasal spray without damaging surfactants. S, Brown Lim NA, Teng O, Ng CYH, Bao LXY, Tambyah PA, Quek AML, Seet RCS. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. (2021) Efficacy of Essential Iodine Drops against Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2). "Iodine derivative kills SARS-CoV-2 within 90 sec". Concomitant use of ocular antimicrobial drugs; concomitant use of ocular formulations containing mercury-based preservatives; preterm neonates. 2020 Aug;29(7):599-603. doi: 10.1111/jopr.13220. Formulation: Spray. while also discussing the various products Sartorius produces in order to aid in this. According to Dr. Adalja, povidone-iodine is commonly used for a gargle for sore throats, but accidentally ingesting itwhether you swallow it by . There are also medicated douchesmade with 0.3% povidone-iodineto help relieve minor vaginal irritation and itching. ALCOHOL FREE FORMULATION; . and transmitted securely. CN1203864C - Spray formulation of providone iodine - Google Amazon.ca: Povidone Iodine Nasal Spray 2020;146(11):1-5. doi:10. .

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