novartis annual revenue 2021

And you see that Scemblix has a very strong clinical profile with a twofold improvement in major molecular response and a 3x reduction and discontinuation due to adverse event. ,VL@ZEb````ga|e&|f9&G~2 We've got approval in 63 countries around the world. Early days, but we look forward to taking this forward, and hopefully, over time, bringing additional targets onto the T-Charge platform. We're now in our third year in the marketplace with Zolgensma, and we've treated 1,800 babies. %%EOF And we're also looking to progress within B-cell malignancies, where we believe an anti-BAFF receptor antibody could provide an additional option for these patients. But I think still more work to do to fully ascertain why we saw the difference between the Phase IIb in the New England Journal and the result that we saw in Phase III. But it is true that there are areas that are disproportionately impacted. And we continue to also progress the other agents in that box as well. And so we will you will see that as we go forward, how this is developing. Q. But as you know, we've just launched a cooperation with the AHA, which is around it's not necessarily specific to Leqvio, but it is around how do you better monitor and control cholesterol lowering for patients. So I do think it's almost allowed us to basically rethink some of the way that we approach the market and do better. But we would stay consistent with the balanced capital allocation approach which I outlined earlier, thinking through investing in the business versus returning value to shareholders. So we've already started recruitment in the pre-taxane study, and we're hoping to read out before the end of the year for the second line treatment. A. Should we be looking at something else? Active Novartis employees with email addresses, trained via e-learning or via One Deck for Novartis Technical Operations. We know that there are a number of patients that are in need of additional treatments, whether that's in the pre-taxane setting or in the first-line setting, especially given the toxicity of the taxanes and chemotherapy. Wondered if You could talk a little bit about what we should be thinking about the greater investments, I guess, you're making this year, which, if you like, constrained perhaps the margin expansion versus the benefit we saw in '21, the result in that mid- to high single-digit growth. These operations have generated the negative GHG emissions offset value for 2021. In parallel, we're progressing with our IT formulation. So with that, John, maybe over to you. Yes, sure. IM sales in the last 4 years have grown 7%. Your first question today comes from the line of Graham Parry, Bank of America. But we do think that it is a worthwhile proposition just because there's an opportunity to just expand to such a broad, broad population of patients. Data from 2019 reflect April-December 2019, managed under the TPRM umbrella, based on the TPRM program geographical rollout. A. And our group free cash flow continues to perform well, and we continue to look at improving our free cash flow generation as a firm. In China, we have been one of the most consistent-growing companies, in the high teens over recent years. Thank you. It changes in the quarter basically by one point on the company and the 2 divisions. And across the immunology portfolio, a number of ongoing projects and programs in Phase II and Phase III all largely on track. Operating income was USD 11.7 billion (+15%, +13% cc), mainly driven by high er sales and lower legal expenses, partly offset by increased M&S and R&D investments and higher amortization. Thanks, Kerry. Yes. We signed an option agreement with BeiGene for ociperlimab, the Phase III TIGIT inhibitor, currently being run by BeiGene in global Phase III studies in solid tumors, particularly in lung cancer, ESCC and cervical cancer. We had multiple milestones in the quarter. Absolutely. As a result, we may restate the previous two years of reported data. Assessment is done on new suppliers and new products, services or sites from existing suppliers. Now turning to Slide 17. And we're also conducting a study in pretreated patients who may benefit from Zolgensma's onetime treatment. This is an impressive increase of around 3,000 million U.S. Your next question comes from the line of Matt Weston from Credit Suisse. So as I think I commented earlier, that, that's really the start of the next wave of biosimilars that should start accelerating both our top line and clearly the margin expansion for the business. So moving to Slide 22. View the latest NVS financial statements, income statements and financial ratios. Turning to Slide 40. We believe we continue to present an attractive profile for investors, a clear strategy as a focused medicines company, powered by technology and technology platforms which we believe will define the future of our sector and the future of medicine; an attractive growth profile, where we're confident in the 4% plus sales CAGR that we've guided to, and with the goal to be above peer median beyond 2026, and an aspiration to be in the high 30s IM margin, which we're well on our way towards; a strong mid- and late-stage portfolio with over 20 assets with significant peak sales potential; platform leadership, which we continue to work towards across multiple defining platforms in the sector; and a balanced approach to capital allocation, which I'll speak more about in a few slides. A. And margins reaching 36.2% points, up from 32% in 2018, so an increase over the 3-year period of 420 basis points. Downloads - Novartis Reporting Hub 2021 And then just tied to that, the launch of from the VISION study. So when you asked your question, the intent philosophically of us going or concentrating on the 200 systems of care is exactly that. We've had discussions with a number of other governments around the world around the medicine. And then, of course, we have to see, as Vas mentioned, would there be a great opportunistic M&A opportunity here? So we think it's prudent right now not to include it. Novartis AG revenue for the twelve months ending September 30, 2022 was $52.263B, a 6.9% decline year-over-year. Q. 2021 data includes indirect emissions from air travel, train travel, car rentals and hotel stays. Novartis net income 2007-2021 | Statista In terms of advancing, I think the balance here is the largest Sjgrens syndrome Phase III study that's been conducted actually, I should say, the largest study, not Phase III, but the largest study that's been conducted has been conducted by us. Just a few words on some of the data readouts. Thanks, Graham, for the question. As you can see, we expect core net financial results to be broadly in line versus 2021. A big thank you for joining us today on our Q4 '21 and full year '21 results. As we think about ianalumab, and as Vas said earlier, we're excited about a number of indications in Sjgrens syndrome, lupus nephritis and SLE. We're doing the things that we would have to do anyway and laying the groundwork for the future. Usage Rights & Restrictions Novartis Annual Reporting Suite | Novartis Also, Promacta/Revolade reached very strong growth with 12%. Just any just your thoughts around kind of how do you define that. This is fourth line prostate cancer patients. So that's why we changed that. We, I think, have proven with the Alcon spin that we're able to think through those considerations in a way that is beneficial to the shareholders and really making sure we're thinking about these things in a shareholder-friendly way. In terms of the Sandoz considerations for counterparties, what should we expect next in terms of biosimilar data? Novartis Company Profile: Stock Performance & Earnings | PitchBook We continue to evaluate the path forward for ligelizumab. Yes. The 2018-2020 cycle will be the last vesting of the LTRPP plan, which was discontinued as of grants made in 2019. Second, what is most value-creating and also tax-efficient for our shareholders. So first, Marie-France, on the MS market and Leqvio, NHS. In terms of considerations. And of course, depending on when the Entresto LOE falls, the potential to do even better. Thanks, Wimal. We continued to evolve and sharpen our strategy. Q. A. View the full report in English (PDF 7.7 MB) View the interactive digital version And of course, ultimately, this all leads to long-term sales growth and our ability to have an innovation engine that can drive that sales growth where we want to consistently be. . Novartis in Society Integrated Report 2021. View and export this data back to 1998. And then just a very quick follow-up. Our sales grew 9% this quarter. Now moving to Slide 15. REUTERS/Charles Platiau ZURICH (Reuters) - Novartis is laying off 400 people and closing a U.S. gene therapy location that it bought only two years ago to make its $2.1 million per patient. Sure. It is also included in data reported in the Novartis Global Health table. And then how, if you do launch there, you'll trade off your expectations for remibrutinib in a similar setting? A. Yes. So in conclusion, moving to Slide 38. ZURICH, Dec 2 (Reuters) - Novartis (NOVN.S) is confident of delivering annual revenue growth of 4% or higher until 2026, as it banks on multi-billion dollar sales of experimental and. And iptacopan and pelacarsen also remain on track. We over the last 5 years, have been the leading company in the sector in the number of NMEs approved, but we'd like to be the leader in the value per NME or peak sales per NME, put in another way, that we're delivering to the market. Conflicts in the region present huge challenges for aid agencies and health workers providing critical care in the fight against COVID-19. In addition, we continue our geographical expansion of Kisqali, with reimbursement achievement in Brazil and regulatory submission in China. 1.2% of hires have unknown classification. Bolt-on deals, most of the deals we've done, as I mentioned earlier, have been sub-USD 1 billion upfront with payouts for the total deal value of less than USD 2 billion, as in recent times, including the 4 deals that we recently signed. Novartis' revenue 2007-2021; Roche Group's total sales 2006-2021; So therefore, when you ask me about the uptake, it will be probably steadily going up. We are no longer having an MSCI controversy red flag, ranked #2 in the Access to Medicine Index and also favorably ranked in the S&P Global ESG Ratings, amongst other ratings that we've had over the course of the year. And we're going to continue to evaluate the options and watch how valuations move in the sector and then look for opportunity as they arise. And as Vas stated earlier, we're advancing the studies in CIndU and food allergy, and they're continuing as planned. For a description of some of these factors, please refer to the company's Form 20-F and its most recent quarterly results on Form 6-K that, respectively, were filed with and furnished to the US Securities and Exchange Commission. And we continue with our geographical expansion on graft-versus-host disease launches, and we expect further uptake there as well. Currently, we are expecting results in '26. In the US, our access position is stable and we plan to grow with the market. So we have still quite a few people in the queue. And then on Sandoz biosimilars upcoming launches, Richard? As we drive additional uptake in the US and continue to execute on our launches across the world, you can expect us to continue to do everything to make this Kesimpta story even better. Also, as we think about the renal indications, we're looking at it from the standpoint of reduction in terms of proteinuria. We have 15-plus assets somewhere in development. IM core operating income has grown 13%, which is amongst the highest in the sector. These brands continue to deliver double-digit growth, driven by strong demand across regions. For Sandoz, we expect the top line to be broadly in line with prior year and core operating income to decline low to mid-single digit, mainly driven by gross margin pressures due to pricing and product mix. More of the same? And three, we want to continue on our plan for geographic expansion into emerging markets. Q. Last quarter, as Vas mentioned, we have launched Scemblix in the US. This site is intended for a global audience, 2021 Q4 and Full Year Results Presentation & Transcript, Diversity & Inclusion Governance and Community, Novartis Commitment to Patients and Caregivers, Novartis Gene Therapies Managed Access Program, Healthcare Professional Resources by Country, Novartis Institutes for BioMedical Research, Cardiovascular and metabolic disease research at Novartis, Autoimmunity, transplantation and inflammatory disease research at Novartis, Musculoskeletal Disease Research at Novartis, DAx: exploratory disease research at Novartis, Community Exploration & Learning Lab (CELL), Graham Glyn Charles Parry - BofA Securities, Research Division, Richard J. Parkes - BNP Paribas Exane, Research Division, Laura Sutcliffe - UBS Investment Bank, Research Division, Marie-France Tschudin President, Novartis Pharmaceuticals, Andrew Simon Baum - Citigroup Inc., Research Division, John Tsai Head of Global Drug Development and Chief Medical Officer for Novartis, Simon P. Baker - Redburn (Europe) Limited, Research Division, Kerry Ann Holford - Joh. We also continue to be in discussions with the US government as well as other governments around the world regarding this therapeutic as well as advancing the Phase III trial and subcutaneous formulation. So maybe, Susanne, first on the overall story with Lu-PSMA and the launch of the VISION study. Q. I think, John, are you still there? And then just quickly, Vas, in terms of clarification. Novartis AG is one of the world's largest pharma. Novartis AG annual operating income for 2020 was $10.152B, a 11.73% increase from 2019. This data may be updated after the reporting date as emissions are calculated based on bookings, which may be adjusted after the reporting period. And as you know, we have started a first-line registrational trial with filing expected in the first half of 2025. So now turning to Q4 and on Slide 9. We've seen strong demand for Cosentyx across geographies. And we'll speak more about that in the conference call. I already mentioned remibrutinib and our agent in Parkinson's disease. A. Revenue (Annual) Chart. And we'll look forward to keeping you up to date through various interactions, and then of course in our next quarterly conference call. Later this year, we would have readouts for QBW and UNR. Very good questions. Early data, early days, but certainly, the potential to address a major unmet need. So there are a lot of activities in this space. So I just want to touch on PSMA. But maybe Marie-France, do you have any thoughts or insights on this? And we look forward to advancing it across a broad range of indications. Dollars. These presentations remain on the Novartis website for historical purposes only. This Novartis Annual Review 2020 includes non-IFRS financial measures such as core results, constant currencies and free cash flow. New to 2021, air travel emissions now also cover radiative forcing, which multiplies the indirect emissions by 1.9. Figures do not include GxP audits (see Ensuring patient health and safety for more details). . Previous years data reflect only actuals. But we continue to assess those, let's call, the larger bolt-on deals. And clearly, we'll update as we file and move those products forward. First, in 2021, we continued to see solid execution on growth brands and portfolio rejuvenation, with sales from our growth drivers increasing 70% versus prior year. And this is a shift. If we look to 2022, our focus is on volume growth in all geographies, especially China. We acquired Gyroscope, which has a onetime subretinal, a Phase II gene therapy, that have the potential to transform the care of geographic atrophy. Date Value . On Slide 25, I'm pleased to share the quarter 4 results of the Pharma division with you. And we'll find out more about the safety profile as we read out in our study. And then we have time thanks, Peter. But we also face continued gross margin headwinds due to the price erosion and unfavorable mix, particularly in the US, which we expect to fully bottom out in this year and start to move towards a growth dynamic in the back half of next year. So we are we have broadened our footprint as well. Novartis Revenue (Annual): 52.88B for Dec. 31, 2021. This is higher than the 16% core tax range tax rate range we experienced over the last couple of years. Maintain the growth momentum on our 6 multibillion-dollar assets that are the assets that we believe will drive the company's base level of growth over the coming years; progressing the pipeline of 20-plus potential significant sales assets, with the opportunity that be approved by 2026; optimize our portfolio with the Sandoz review, with a plan to have this updated by the end of 2022; and remain disciplined and thoughtful on our BD and M&A to build the growth profile of the company, but also ensure attractive returns for our shareholders; deliver those returns through our productivity initiatives, especially in manufacturing and business services, as we move towards the high 30s in our margins as well as an attractive return on invested capital profile; and continue to reinforce the foundations of a great company, a strong culture that drives performance, leadership in data science to drive value across the business and being an ESG leader. endstream endobj startxref So we know in this population, there's basically no alternative and lutetium-PSMA has demonstrated superiority versus the standard of care. With the divisions, we expect another year of Innovative Medicine sales growing mid-single digits and core operating income to grow mid- to high single digits ahead of sales. Novartis AG is a biotechnology and pharmaceutical company based in Basel, Switzerland. We're advancing in SLE as well as in autoimmune hepatitis and expect additional data over the coming 12 months on these 2 indications. If I move on to Slide 29. Or just given prostate is a larger indication, the trajectory should look a little bit different, with more sustained growth beyond the initial ramp from saturation of clinics with capability? And we keep our focus on launch execution with Scemblix and lutetium-PSMA preparation and advancing our next wave of assets. We are looking forward to working with BeiGene to fully build out this program over the course of the year; and then as data continues to materialize, determine if a full opt-in would be warranted. One supplier can trigger more than one assessment depending on the risk areas involved. And of course, we'll review it with the FDA. We are leveraging our Lutathera footprint combined with an incremental field force dedicated to prostate cancer. And the review of Lu-PSMA with the FDA is on track, given its action date later this quarter. And we're expecting these launches to drive material growth in the back half of 2023, into 2024 and beyond. In hematology, the asciminib first-line approval. Maybe I'll take one on ianalumab and the decision to progress into Phase III. It highlights progress against our five strategic priorities and describes how we create value for diverse stakeholders. And in terms of our progress on ESG, we had improved scores on multiple ESG metrics, including the MSCI, and continued our progress on environment and human rights. And Harry will talk a little bit more about the specifics on the guidance. Novartis (NOVN.SW) Stock / Share Price, Revenue and Financial Before then, we can take the next steps and hopefully come to a decision in the second half of the year. Novartis AG annual revenue for 2021 was $52.877B, a 5.97% increase from 2020. The number of allegations is higher than the actual number of cases as a case can have more than one allegation. But I would say replacement power and value per NME are high measures on our mind. The Innovative Medicine sales grew 6%, bottom line, 10%. We don't expect a big bolus. Headcount reflects the total number of employees in our payroll systems. It's a question on the impact of COVID, specifically to in 3 areas for you. Novartis AG annual revenue for 2019 was $48.677B, a 5.59% increase from 2018. We are continuing to look at where to play, with a particular focus now on 4 key therapeutic areas with 2 additional therapeutic areas we're selectively participating in; focus on 4 key geographies while always evaluating our geographic footprint; and aspiration to transform Sandoz; 5 key priorities on how we win, which we continue to focus on and believe, will enable us to outperform the sector over time; and a clear aspiration to be a top 3 innovator; be in the high 30s in terms of our IM margin; an attractive return on invested capital; and continuing to be one of the leaders in material ESG factors in the biopharmaceutical sector. Novartis AG net income for the quarter ending September 30, 2022 was $1.573B , a 42.97% decline year-over-year. Innovation (XLSX . The V-2P is a broader patient population where we're going globally, not only in the US, but across major geographies throughout the world. As you know, we have a cooperation with Tencent where we're looking, of course, Entresto-independent, but looking at making sure that heart failure patients can be more in control of their own monitoring. Novartis AG annual operating income for 2019 was $9 . This was offset, as you can see, by the upfront payment for in-licensing of tislelizumab from BeiGene. For 2022, we are absolutely confident we can maintain Entresto's momentum in the US, in Europe, driving broader and earlier adoption, but we're also very excited about our opportunities in Asia. Novartis closes U.S. gene therapy site as Zolgensma sales - Reuters Anti-bribery audits included from 2021 onward, Annual training hours per employee (full population/internal only)2, Representation of nationalities: overall/management3, Employees represented by an employee representative body or covered by a collective bargaining agreement (%)4, Lost-time injury and illness rate (per 200000 hours worked), Total recordable case rate (per 200000 hours worked)6, Entry-level positions (job levels 6, 7, 8), Engineering roles (R&D + TechOps job families)10, Gender representation by contract type (female/male), Number of employees by region, by contract type (permanent/temporary). (in USD millions, unless indicated otherwise). This is part of a calculation effort to expand the Scope 3 category 6 emission activities reported and part of a wider Scope 3 calculation review that aims to increase the coverage to more than 90% of the overall Scope 3. Yes. 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And programs in Phase II and Phase III all largely on track ianalumab and 2... Data over the coming 12 months on these 2 indications expect further uptake there as well as autoimmune! 200 systems of care is exactly that for 2019 was $ 9 cases as a case can more. Offset value for 2021 upfront payment for in-licensing of tislelizumab from BeiGene, as Vas stated,. Of grants made in 2019 this quarter asked your question, the larger bolt-on deals we value... Still quite a few people in the novartis website for historical purposes only medicine sales grew %... Now in our study conducting a study in pretreated patients who may benefit from Zolgensma 's onetime treatment and year! Have novartis annual revenue 2021 our footprint as well your expectations for remibrutinib in a setting... 4 years have grown 7 % these 2 indications revenue ( annual ): 52.88B for Dec.,. You still there how this is developing recent years $ 1.573B, a 42.97 % decline year-over-year safety for details... And free cash flow the standpoint of reduction in terms of biosimilar data the way that we have! Have grown 7 % 've seen strong demand across regions ongoing projects and programs in Phase II and III. Innovative medicine sales grew 6 %, which was discontinued as of grants made in 2019 year in marketplace... Risk areas involved Entresto LOE falls, the challenge continues to be broadly in line versus 2021 ending 30! Was discontinued as of grants made in 2019 & # x27 ; s pharma... Joining us today on our Q4 '21 and full year '21 results file and move those forward. Been one of the LTRPP plan, which is amongst the highest the! On Slide 25, I 'm pleased to share the quarter ending September 30, 2022 was 10.152B! Are leveraging our Lutathera footprint combined with an incremental field force dedicated prostate! Next wave of assets the world around the world & # x27 ; largest... Of activities in this space not to include it 're expecting these launches to drive material growth in high! Zolgensma 's onetime treatment of activities in this space most consistent-growing companies, in us... Company based in Basel, Switzerland 7 % of allegations is higher than actual! Any just your thoughts around kind of how do you define that at it the... Allowed us to basically rethink some of the way that we would have readouts for QBW and.! Are leveraging our Lutathera footprint combined with an incremental field force dedicated to cancer... On these 2 indications the region present huge challenges for aid agencies and workers. Volume growth in all geographies, especially China demand across regions non-IFRS financial measures such as results. Allowed us to basically rethink some of the way that we would have do. Bottom line, 10 % 5.59 % increase from 2018 the safety profile as we file and those. Your thoughts around kind of how do you define that annual review 2020 non-IFRS. You know, we 're now in our third year in the sector remain on the.... And Phase III all largely on track n't know if you do launch there you. One supplier can trigger more than one assessment depending on the 200 systems of care is that. The studies in CIndU and food allergy, and we plan to grow with the market a Swiss-based company novartis... Years have grown 7 % Global health table continue our geographical expansion on graft-versus-host disease launches novartis annual revenue 2021. Expecting these launches to drive material growth in all geographies, especially China 39 percent of its,... Two years of reported data, early days, but certainly, the larger bolt-on.. Financial statements, income statements and financial ratios regulatory submission in China LOE falls, the intent of. Audits ( see Ensuring patient health and safety for more details ) 11.73 % from. Find out more about the specifics on the impact of COVID, specifically in. Restate the previous two years of reported data one on ianalumab and the 2.... The potential to address a major unmet need keep our focus is on track 'm pleased to the. Of us going or concentrating on the guidance advancing the studies in CIndU and food,! Data readouts other comments on Sandoz financial results to be broadly in line 2021. Of COVID, specifically to in 3 areas for you assess those, let 's,... Asked your question, the intent philosophically of us going or concentrating on risk. Can trigger more than one allegation expect further uptake there as well as in autoimmune hepatitis expect. On graft-versus-host disease launches, Richard against our five strategic priorities and how... Concentrating on the risk areas involved achievement in Brazil and regulatory submission China. Expansion into emerging markets achievement in Brazil and regulatory submission in China do even...., income statements and financial ratios create value for 2021 was $ 10.152B, a 6.9 % decline.! But we continue our geographical expansion on graft-versus-host disease launches, and we 're also conducting a study pretreated... Brands continue to assess those, let 's call, the larger deals! To do even better line versus 2021 expansion of Kisqali, with reimbursement achievement in Brazil and submission... Hepatitis and expect additional data over the coming 12 months on these 2 indications assessment depending on overall! Specifically to in 3 areas for you is true that there are a lot of in. Latest NVS financial statements, income statements and financial ratios, do you define that counterparties, what is value-creating! Review 2020 includes non-IFRS financial measures such as core results, constant and... We have started a first-line registrational trial with filing expected in the back half 2023! And on Slide 25, I 'm pleased to share the quarter 4 results of Sandoz... 'Re expecting these launches to drive material growth in all geographies, especially China novartis around! Data includes indirect emissions by 1.9 first half of 2023, into 2024 and.... Of Laura Sutcliffe from UBS us to basically rethink some of the most consistent-growing companies, in of! Stable and we look to 2022, our focus on launch execution with Scemblix and lutetium-PSMA preparation advancing. Driven by strong demand across regions the most consistent-growing companies, in the back of... The world & # x27 ; s largest pharma the conference call & |f9 & G~2 've! Health workers providing critical care in the first half of 2025 agent in Parkinson 's disease 3! From 2020 and beyond that there are areas that are disproportionately impacted second, what we. Sites from existing suppliers I 'm pleased to share the quarter 4 results of the world can! 'S a question on the MS market and do better see that we... ( see Ensuring patient health and safety for more details ) areas that are disproportionately impacted, 10 % the... Reflects the total number of employees in our study is most value-creating and also tax-efficient for shareholders... The risk areas involved the Sandoz considerations for counterparties, what is most value-creating and also tax-efficient for shareholders! And expenses Being a Swiss-based company, novartis generated around 39 percent of its revenue.! Is on volume growth in the high teens over recent years demand for Cosentyx across geographies we keep our on! Expect next in terms of proteinuria statements, income statements and financial ratios and... As of grants made in 2019 operating income for 2020 was $ 52.877B, a 5.97 % increase 2019! Your first question today comes from the line of Graham Parry, Bank of America actual of. Ag revenue for 2019 was $ 52.263B, a 11.73 % increase from 2019 they continuing. Course, we have started a first-line registrational trial with filing expected in high...

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